MarkIt: A Collaborative Artificial Intelligence Annotation Platform Leveraging Blockchain For Medical Imaging Research

Jan Witowski Orcid logo ,
Jan Witowski
Jongmum Choi ,
Jongmum Choi
Soomin Jeon Orcid logo ,
Soomin Jeon
Doyun Kim Orcid logo ,
Doyun Kim
Joowon Chung Orcid logo ,
Joowon Chung
John Conklin Orcid logo ,
John Conklin
Maria Gabriela Figueiro Longo Orcid logo ,
Maria Gabriela Figueiro Longo
Marc D. Succi Orcid logo ,
Marc D. Succi
Synho Do Orcid logo
Synho Do

Published: 21.10.2022.

Biochemistry

Volume 4, Issue 1 (2021)

https://doi.org/10.30953/bhty.v4.176

Abstract

Current research on medical image processing relies heavily on the amount and quality of input data. Specifically, supervised machine learning methods require well-annotated datasets. A lack of annotation tools limits the potential to achieve high-volume processing and scaled systems with a proper reward mechanism. We developed MarkIt, a web-based tool, for collaborative annotation of medical imaging data with artificial intelligence and blockchain technologies. Our platform handles both Digital Imaging and Communications in Medicine (DICOM) and non-DICOM images, and allows users to annotate them for classification and object detection tasks in an efficient manner. MarkIt can accelerate the annotation process and keep track of user activities to calculate a fair reward. A proof-of-concept experiment was conducted with three fellowship-trained radiologists, each of whom annotated 1,000 chest X-ray studies for multi-label classification. We calculated the inter-rater agreement and estimated the value of the dataset to distribute the reward for annotators using a crypto currency. We hypothesize that MarkIt allows the typically arduous annotation task to become more efficient. In addition, MarkIt can serve as a platform to evaluate the value of data and trade the annotation results in a more scalable manner in the future. The platform is publicly available for testing on https://markit.mgh.harvard.edu.

Keywords

References

1.
Abaho M, Bollegala D, Williamson P, Dodd S. Correcting crowdsourced annotations to improve detection of outcome types in evidence based medicine. 2019;
2.
Greenspan H, van Ginneken B, Summers RM. Guest Editorial Deep Learning in Medical Imaging: Overview and Future Promise of an Exciting New Technique. IEEE Transactions on Medical Imaging. 2016;35(5):1153–9.
3.
Albarqouni S, Baur C, Achilles F, Belagiannis V, Demirci S, Navab N. AggNet: Deep Learning From Crowds for Mitosis Detection in Breast Cancer Histology Images. IEEE Transactions on Medical Imaging. 2016;35(5):1313–21.
4.
Abujudeh HH, Boland GW, Kaewlai R, Rabiner P, Halpern EF, Gazelle GS, et al. Abdominal and pelvic computed tomography (CT) interpretation: discrepancy rates among experienced radiologists. European Radiology. 2010;20(8):1952–7.
5.
Raykar V, Yu S, Zhao L, Jerebko A, Florin C, Valadez G. Supervised learning from multiple experts: whom to trust when everyone lies a bit. Proc Int Conf Mach Learn. 2009;
6.
Raykar V, Yu S, Zhao L, Valadez G, Florin C, Bogoni L. Learning from crowds. J Mach Learn Res. 2010;(4):1297–322.
7.
Yan Y, Rosales R, Fung G, Schmidt M, Hermosillo G, Bogoni L. Modeling annotator expertise: learning when everybody knows a bit of something. 2010;
8.
Raykar V, Yu S. Eliminating spammers and ranking annotators for crowdsourced labeling tasks. J Mach Learn Res. 2012;(1):491–518.
9.
Tanno R, Saeedi A, Sankaranarayanan S, Alexander D, Silberman N. Learning from noisy labels by regularized estimation of annotator confusion. 2019;
10.
Jodogne S. The Orthanc Ecosystem for Medical Imaging. Journal of Digital Imaging. 2018;31(3):341–52.
11.
Irvin J, Rajpurkar P, Ko M, Yu Y, Ciurea-Ilcus S, Chute C. Chexpert: a large chest radiograph dataset with uncertainty labels and expert comparison. 2019;(01):590–7.
12.
Wang X, Peng Y, Lu L, Lu Z, Bagheri M, Summers R. Chestxray8: hospital-scale chest x-ray database and benchmarks on weakly-supervised classification and localization of common thorax diseases. 2017;
13.
Selvaraju R, Cogswell M, Das A, Vedantam R, Parikh D, Batra D. Grad-cam: visual explanations from deep networks via gradient-based localization. 2017;
14.
Demirer M, Candemir S, Bigelow MT, Yu SM, Gupta V, Prevedello LM, et al. A User Interface for Optimizing Radiologist Engagement in Image Data                    Curation for Artificial Intelligence. Radiology: Artificial Intelligence. 2019;1(6):e180095.
15.
Rubin DL, Akdogan MU, Altindag C, Alkim E. ePAD: An Image Annotation and Analysis Platform for Quantitative Imaging. Tomography. 2019;5(1):170–83.
16.
Urban T, Ziegler E, Lewis R, Hafey C, Sadow C, Van den Abbeele AD, et al. LesionTracker: Extensible Open-Source Zero-Footprint Web Viewer for Cancer Imaging Research and Clinical Trials. Cancer Research. 2017;77(21):e119–22.
17.
Philbrick KA, Weston AD, Akkus Z, Kline TL, Korfiatis P, Sakinis T, et al. RIL-Contour: a Medical Imaging Dataset Annotation Tool for and with Deep Learning. Journal of Digital Imaging. 2019;32(4):571–81.
18.
Chen S, Guo J, Wang C, Xu X, Yi Z, Li W. DeepLNAnno: a Web-Based Lung Nodules Annotating System for CT Images. Journal of Medical Systems. 2019;43(7).
19.
Abdullah S, Rothenberg S, Siegel E, Kim W. School of Block–Review of Blockchain for the Radiologists. Academic Radiology. 2020;27(1):47–57.

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